Participants will have to complete a series of mental and physical challenges - as individuals or in teams of three.  Physically, they will cover a marathon distance (26.2 miles) by foot, bike and boat over the course of the weekend.  The mental challenges will require logic, problem solving abilities, a good memory and most importantly, perseverance.  

The event will take place on the stunning banks of Lake Windermere in the Lake District on 10th and 11th October, but that is all that the organisers are willing to reveal for now.  One of the unique concepts of the 24seven Challenge is that more clues about the weekend are revealed as entrants reach set fundraising targets.  Many elements will, however, remain a mystery until the start of the event.

The first 24seven Challenge in 2008 saw 68 people raise over £41,000 for CLIC Sargent.   Many of them enjoyed the experience so much that they are signing up to do it all over again - like Liz Williams, a Mum of three from Cheltenham.  Liz signed up for the event both for the physical and mental challenge and to raise money for the charity that supported her family while her daughter Grace battled with leukaemia.   

She said: "I'm doing the challenge again because every day we are thankful that our daughter is still in remission. The best way to say thanks to CLIC Sargent is to help them to continue to support families like mine. If I manage to raise more money than last year then I'll be happy. Of course I want to do better than 3rd - not that I'm competitive!

"I'm hoping the getting fit bit will be easier this year, as I think I know what I'm in for, although there is every chance that I don't!  Whatever happens, if it's anything like last year, it will be tremendous fun."

Ben Harrison, a student from Nottingham, 23, heard about the event through a friend who took part last year.  He said: "This event sounds awesome.  It has everything - running, cycling, and mind bending puzzles - the lot!  I like keeping fit and I know from past visits that there aren't many better locations in the UK than the Lake District for being out and about.

"I'm entering this mainly for the challenge, but the fact I get to help a brilliant charity while having a crazy adventure, just makes it even better!"

The 24seven concept aims to represent the 24 hours a day, seven days a week support that CLIC Sargent, the children's cancer charity, provide for families affected by childhood cancer and as a result struck a chord with participants and event staff alike.

Beverley Mackenzie, Challenge Events Manager for CLIC Sargent said: "Last year's event was fantastic!  Everyone involved had great fun and achieved a great deal of satisfaction from completing - or should I say surviving - the weekend. 

"I'm even more excited about this year though.  We've changed the challenges and the location and we hope to have lots more people from different walks of life taking part.  It's great to see people like Liz returning for the second year running as it shows that she had a great time!  The most important challenge is to raise as much money as possible to help families whose lives have been turned upside down by childhood cancer.  Every penny raised really can make a big difference."

The venue is ready, the date is set and the goal is clear - raising money for children and young people with cancer, and their families.  Entries are now open, so make sure you secure your place by visiting www.24sevenchallenge.co.uk today.

October 10th/11th is THE must do weekend of 2009.